NOBOX - No Box

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Homeobox protein NOBOX, also known as newborn ovary homeobox protein, is a protein that in humans is encoded by the NOBOX gene.


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Function

NOBOX is a homeobox gene that is preferentially expressed in oocytes. In mice, it is essential for folliculogenesis and regulation of oocyte-specific genes.


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Clinical significance

A mutation in the NOBOX gene is associated with premature ovarian failure.

Source of the article : Wikipedia



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